Modeling Longitudinal Voxelwise Feature Change in Normal Aging with Spatial-Anatomical Regularization

Image voxel/vertex-wise feature in the brain is widely used for automatic classification or significant region detection of various dementia syndromes. In these studies, the non-imaging variables, such as age, will affect the results, but may be uninterested to the clinical applications. Imaging data can be considered as a combination of ...More