An infrastructure for precision medicine through analysis of big data.

Marco Moscatelli,Andrea Manconi, Mauro Pessina,Giovanni Fellegara, Stefano Rampoldi,Luciano Milanesi, Andrea Casasco,Matteo Gnocchi

BMC Bioinformatics(2018)

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摘要
The infrastructure allows the integration of multiple and heterogeneous sources of anonymized data from the different clinical platforms. Both unstructured and semi-structured data are processed to obtain a precise historical analysis of the clinical activities of one or more patients. Data aggregation allows to perform a series of statistical assessments required to answer complex questions that can be used in a variety of fields, such as predictive and precision medicine. In particular, studying the clinical history of patients that have developed similar pathologies can help to predict or individuate markers able to allow an early diagnosis of possible illnesses.
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关键词
Big data,Clinical decision support systems,Machine learning,Medical record,NoSQL
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