An Efficient Multiple Sclerosis Segmentation and Detection System Using Neural Networks

In this work, an efficient multiple sclerosis (MS) segmentation technique is proposed to simplify pre-processing steps and diminish processing time using heterogeneous single-channel magnetic resonance imaging (MRI). A spatial-filtering image mapping, histogram reference image, and histogram matching techniques are effectively applied to possess a local threshold per image using the global threshold algorithm. Feature extraction is performed using mathematical and morphological operations, and a multilayer feed-forward neural network (MLFFNN) is used identify multiple sclerosis' tissues. Fluid-attenuated inversion recovery (FLAIR) series are used to integrate a faster system while maintaining reliability and accuracy. A sagittal (SAG) FLAIR based system is proposed for the first time in MS detection systems, which reduces the number of utilized images, and decreases the processing time by nearly one-third. Our detection system provided a significant recognition rate of up to 98.5%. Moreover, a relatively high dice coefficient (DC) value (0.71 +/- 0.18) was observed upon testing new images.