Retina-derived POU domain factor 1 coordinates expression of genes relevant to renal and neuronal development.

Antonio Fiorino,Giacomo Manenti,Beatrice Gamba,Gabriele Bucci,Loris De Cecco,Michele Sardella,Giacomo Buscemi,Sara Ciceri,Maria T Radice,Paolo Radice,Daniela Perotti

The International Journal of Biochemistry & Cell Biology（2016）

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摘要

⿢RPF-1 regulates developmental genes through binding to promoter consensus sites.⿢Its ectopic expression decreases cell proliferation.⿢Neuronal and renal specification relevant genes are controlled by RPF-1.⿢The study suggests a role for RPF-1 transcription factor in developmental programs.

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关键词

c-dbAMP,Dxy,FC,G4,GO,HSV,MDCK,MM,NPC,WT,PAA,qRT,RT-PCR,TAD,TF,tRA,Tet,TSS,WB

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