Quantitative Analysis of Kynurenine Aminotransferase II in the Adult Rat Brain Reveals High Expression in Proliferative Zones and Corpus Callosum.

Chang Song,Sarah M Clark,Chloe N Vaughn,James D Nicholson,Kelley J Murphy,Ta-Chung M Mou,Robert Schwarcz,Gloria E Hoffman,Leonardo H Tonelli

Neuroscience（2018）

引用 16|浏览27

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摘要

•KAT II in the brain is expressed with a region specific pattern.•KAT II is expressed with the highest levels in germinal zones.•KAT II in these regions is specific for astrocytes.•KAT II mRNA in the subventricular zone is responsive to peripheral immune challenge.

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关键词

AADAT,cc,DAB,DCX,GFAP,IWMNs,KAT II/AADAT,KP,KYNA,LPSs,ME,PBS,RMS,SGZ,SSC,SVZ,α7nACh

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