The Use of Bile Salt Micelles for the Prediction of Human Intestinal Absorption

Laura J Waters

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Dina S Shokry

Gareth M B Parkes

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John C Mitchell

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Journal of Pharmaceutical Sciences, pp. 3611-3614, 2016.

Cited by: 0|Views14

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Keywords:

human intestinal absorptionHIAsolubilizationUVbile salts

Abstract:

Human intestinal absorption (HIA) will dictate biopharmaceutical performance through its influence on absorption, distribution, metabolism, and elimination and can vary significantly depending upon the nature of the compound under consideration. In this study, an in vitro assay method is proposed for the prediction of HIA through the meas...More

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