Elevated Pre-Antiretroviral Therapy CD39+CD8+ T Cell Frequency Is Associated With Early Mortality in Advanced Human Immunodeficiency Virus/Tuberculosis Co-infection.

Shruthi Ravimohan,Neo Tamuhla,Kebatshabile Nfanyana,Houping Ni,Andrew P. Steenhoff,Robert Gross,Drew Weissman,Gregory P. Bisson

CLINICAL INFECTIOUS DISEASES（2017）

引用 8|浏览13

暂无评分

摘要

Correlates of death soon after antiretroviral therapy (ART) initiation remain unclear. We investigated the association between expression of CD39, a novel immune exhaustion marker, and early mortality in patients with human immunodeficiency virus/tuberculosis co-infection. Elevated pre-ART CD39(+)CD8(+) T cell frequency was independently associated with mortality within 6 months of ART initiation.

查看译文

关键词

HIV,tuberculosis,early mortality,CD39,CD8(+) T cells

AI 理解论文

溯源树

样例

生成溯源树，研究论文发展脉络

Chat Paper

正在生成论文摘要