Dramatic psychiatric and behavioral symptoms following a subthalamic lesion.

•Neuropsychiatric symptoms following a subthalamic lesion have been rarely reported.•Subthalamic nucleus is part of the limbic circuitry associated with emotion and behavior.•Severe neuropsychiatric symptoms can occur from subthalamic lesion, and can be troubling.•Neuropsychiatric symptoms require more attention in the patients with a subthalamic lesion.