Senescence-associated reprogramming promotes cancer stemness

NATURE（2017）

引用 632|浏览44

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摘要

Cellular senescence induced by chemotherapy leads to the acquisition of stemness in cancer cells, which results in enhanced tumour-promoting capacity after forced release or spontaneous escape from the senescent cell-cycle arrest.

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关键词

B-cell lymphoma,Cancer stem cells,Mechanisms of disease,Senescence,Science,Humanities and Social Sciences,multidisciplinary

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