Apolipoprotein L1 Variants and Blood Pressure Traits in African Americans.

Girish N Nadkarni,Geneviève Galarneau,Stephen B Ellis,Rajiv Nadukuru,Jinglan Zhang,Stuart A Scott,Claudia Schurmann,Rongling Li,Laura J Rasmussen-Torvik,Abel N Kho,M Geoffrey Hayes,Jennifer A Pacheco,Teri A Manolio,Rex L Chisholm,Dan M Roden,Joshua C Denny,Eimear E Kenny,Erwin P Bottinger

Journal of the American College of Cardiology（2017）

引用 43|浏览61

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摘要

APOL1 risk alleles are associated with higher SBP and earlier hypertension diagnoses in young AAs; this relationship appears to follow an additive model.

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关键词

allele,APOL1,estimated glomerular filtration rate,genetic association studies,kidney disease

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