Aspergillus fumigatus alkaline protease 1 (Alp1/Asp f13) in the airways correlates with asthma severity.

Trisha Basu,Seyedmojtaba Seyedmousavi,Janyce A Sugui,Nariman Balenga,Ming Zhao,Kyung Joo Kwon Chung,Sabrina Biardel,Michel Laviolette,Kirk M Druey

Journal of Allergy and Clinical Immunology（2018）

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摘要

Summary A fungal protease (Alp1/ Asp f13 ) from Aspergillus fumigatus was detected in the airways of subjects with asthma but not controls, which correlated strongly with disease severity, respiratory dysfunction, and steroid use.

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