Distinct MET Protein Localization Associated With MET Exon 14 Mutation Types in Patients With Non–small-cell Lung Cancer

Tian Qiu,Weihua Li,Tongtong Zhang,Puyuan Xing,Wenting Huang,Bingning Wang,Lixia Chu,Lei Guo,Xiuyun Liu,Yan Li,Jianming Ying,Junling Li

Clinical Lung Cancer（2018）

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摘要

Distinct MET protein localization is associated with MET exon 14 mutation types in patients with NSCLC. Different MET exon 14 mutation types were identified in a subset of Chinese patients with NSCLC who could possibly benefit from MET targeted therapy.

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关键词

Chinese,Immunohistochemistry,MET exon 14 skipping,Sequencing,Targeted therapy

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