Delayed-Start Analyses in the Phase 3 Solanezumab EXPEDITION3 Study in Mild Alzheimer's Disease.

H Liu-Seifert,M G Case,S W Andersen,K C Holdridge,P S Aisen,S Kollack-Walker,E Siemers

The journal of prevention of Alzheimer's disease（2018）

引用 7|浏览39

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摘要

Delayed-start statistical methodology was used to understand the longitudinal outcomes in EXPEDITION3 and its extension. The small treatment differences observed at the end of the placebo-controlled phase prevented adequate assessment of any putative disease modifying effect.

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关键词

Alzheimer’s disease,cognition,delayed-start analysis,function

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