Antibody Drug Treatment for Steroid-Resistant Rejection After Pediatric Living Donor Liver Transplantation: A Single-Center Experience.
Transplantation Proceedings(2018)
摘要
•The effectiveness of ATG after pediatric LDLT has not yet been reported.•The median concentration of ALT significantly declined from 193.5 (range, 8–508) to 78 (range, 9–655) mU/mL in the antibody drug group after treatment (P = .012), and the median RAI significantly declined from 5 (range, 2–9) to 1 (range, 0–9) (P = .004).•After antibody drug treatment, 12 patients had CMV infections, 2 patients had EBV infections, 3 patients had respiratory infections, and 1 patient had encephalitis. The cause of death in 1 patient with SRR was recurrence of infant fulminant hepatic failure.•Antibody drug treatment for SRR after pediatric LDLT is safe and effective.
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关键词
transplantation,donor,antibody,steroid-resistant,single-center
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