A deamidated interferon-β variant binds to integrin αvβ3.

Renato Mastrangeli,Fabio D'amici,Cosimo-Walter D'Acunto,Sabrina Fiumi,Mara Rossi,Mariagrazia Terlizzese,Wolf Palinsky,Horst Bierau

Cytokine（2018）

引用 5|浏览14

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摘要

•Interferon-beta contains a sequence motif prone to deamidation.•Deamidation generates the DGR and iso-DGR motifs.•Deamidated interferon-beta binds integrin αvβ3 with nanomolar affinity.

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关键词

Interferon-β,Deamidation,Integrin,αvβ3,iso-DGR

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