Circulating Tumor Dna As A Liquid Biopsy In Plasma Cell Dyscrasias

Bernhard Gerber,Martina Manzoni, Valeria Spina,Alessio Bruscaggin, Marta Lionetti,Sonia Fabris, Marzia Barbieri,Gabriella Ciceri,Alessandra Pompa, Gabriela Forestieri, Erika Lerch,Paolo Servida,Francesco Bertoni,Emanuele Zucca,Michele Ghielmini,Agostino Cortelezzi, Franco Cavalli,Georg Stussi, Luca Baldini, Davide Rossi,Antonino Neri

HAEMATOLOGICA（2018）

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摘要

Multiple myeloma (MM) is a clinically and genetically heterogeneous malignant proliferation of plasma cells (PCs) with a typical multifocal distribution in the bone marrow (BM) and occasional extra-medullary dissemination.[1][1] Advances in the genetic knowledge of MM are increasingly translated

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