Vitamin K epoxide reductase expression and prostate cancer risk.

Ben Yi Tew,Sumanta K Pal,Miaoling He,Tommy Tong,Huiqing Wu,JoAnn Hsu,Xueli Liu,Susan L Neuhausen,Jeremy O Jones

Urologic Oncology: Seminars and Original Investigations（2017）

引用 4|浏览16

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摘要

•Vitamin K epoxide reductase (VKOR) is expressed in benign prostate tissue.•VKOR expression is lost in prostate cancer.•VKOR SNPs are associated with higher risk of prostate cancer diagnosis.•VKOR may mediate the anti-prostate cancer effects of warfarin.•Larger multi-institutional cohort studies are warranted.

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关键词

Prostate cancer,Vitamin K epoxide reductase,Warfarin

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