Phase I Trial of Total Marrow and Lymphoid Irradiation Transplantation Conditioning in Patients with Relapsed/Refractory Acute Leukemia.
Biology of Blood and Marrow Transplantation（2017）
摘要
•The total marrow and lymphoid irradiation/cyclophosphamide/etoposide conditioning regimen is safe up to a dose of 2000 cGy•Radiation to off-target critical organs is lower than typically delivered by total body irradiation•The results showed an acceptable risk for graft-versus-host disease and were encouraging for disease control
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关键词
Total marrow and lymphoid irradiation,Acute myeloid leukemia,Acute lymphoblastic leukemia,Relapsed/refractory
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