2877 Characterization of PD-L1 expression and immune cell infiltration in Nasopharyngeal Cancer (NPC)

Oral Oncology(2015)

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摘要
•Programmed death-ligand 1 (PD-L1) is commonly expressed in nasopharyngeal cancer.•PD-L1 expression assessed by IHC was not prognostic for clinical benefit in NPC.•PD-L1 expression/CD8 infiltration were reduced in most post SoC treatment biopsies.•These results provide valuable data for future studies of checkpoint inhibitors.
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关键词
AJCC,FFPE,HE,HLA,HR,IC,IHC,NPC,NSCLC,OS,PD-1,PD-L1,PFS,TC,Th1
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