Combined Analysis of Mifepristone for Psychotic Depression: Plasma Levels Associated With Clinical Response.

Thaddeus S Block,Harvey Kushner,Ned Kalin,Craig Nelson,Joseph Belanoff,Alan Schatzberg

Biological Psychiatry（2018）

引用 55|浏览22

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摘要

A high mifepristone plasma level carried the strongest association with response, followed by changes in adrenocorticotropin hormone and cortisol. Therapeutic plasma levels of mifepristone were most likely to be achieved with the 1200 mg/day dose.

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关键词

Combined analysis,Glucocorticoid receptor,HPA axis,Mifepristone,Plasma level,Psychotic depression

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