Impaired fast network oscillations and mitochondrial dysfunction in a mouse model of alpha-synucleinopathy (A30P).

Emma Robson,Clare Tweedy,Nelson Manzanza,John-Paul Taylor,Peter Atkinson,Fiona Randall,Amy Reeve,Gavin J Clowry,Fiona E N LeBeau

Neuroscience（2018）

引用 12|浏览9

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摘要

•Age-dependent impairment in hippocampal gamma frequency activity in A30P mice.•Gamma oscillations in slices from A30P mice show greater sensitivity to rotenone.•Age-dependent impairment in mitochondrial function in A30P.

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ACSF,AD,ANOVA,CA1/CA3,COX,DAB,DG,DLB,EEG,EPSCs,Hz,IQR,KCN,mtDNA,NBT,NMDA,PBS,PD,PDD,PMS,PV,r.m.p.,RGB,s.e.m.,SDH,α-syn

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