Genetic Characterization of Enterovirus A71 Circulating in Africa.

Maria Dolores Fernandez-Garcia,Romain Volle,Marie-Line Joffret,Serge Alain Sadeuh-Mba,Ionela Gouandjika-Vasilache,Ousmane Kebe,Michael R Wiley,Manasi Majumdar,Etienne Simon-Loriere,Anavaj Sakuntabhai,Gustavo Palacios,Javier Martin,Francis Delpeyroux,Kader Ndiaye,Maël Bessaud

EMERGING INFECTIOUS DISEASES（2018）

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摘要

We analyzed whole-genome sequences of 8 enterovirus A71 isolates (EV-A71). We confirm the circulation of genogroup C and the new genogroup E in West Africa. Our analysis demonstrates wide geographic circulation and describes genetic exchanges between EV-A71 and autochthonous EV-A that might contribute to the emergence of pathogenic lineages.

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Africa,acute flaccid paralysis,enterovirus,enterovirus A71,phylogenetic analysis,recombination,viruses,whole-genome analysis

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