[Surgical treatment of secondary liver malignancies].

Surgical treatment of liver metastases, under certain conditions, can be a step of a multidisciplinary treatment strategy for advanced malignant disease. Nevertheless, it is not the same if metachronous or synchronous metastases are planned to be treated. Indications for surgery are the most clearly defined and accepted in cases of colorectal and neuroendocrine liver metastases. At the same time, the steps of the traditional oncotherapy has changed in the management of synchronous colorectal metastases: the novel concept of the treatment strategy is removing the liver metastases before the colorectal primary. The role of surgery is less clear and defined in the management of metastases from other, non-colorectal and non-neuroendocrine primaries. The main purpose is to evaluate which kind of criteria should be fulfilled to indicate the resection of liver metastases, which are the conditions that, when present, may provide a benefit to a patient from surgery, improving survival. These criteria have not been clarified precisely yet; randomized prospective trials are needed. Consensus recommendations in such cases could be determined based on the results of the mentioned trials.