Is HLA the cause of the high incidence of type 1 diabetes in the Canary Islands? Results from the Type 1 Diabetes Genetics Consortium (T1DGC).

Angelo Santana Del Pino,Nathan Medina-Rodríguez,Marta Hernández-García, Francisco J Nóvoa-Mogollón,Ana M Wägner

Endocrinología, Diabetes y Nutrición (English ed.)（2017）

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摘要

The high incidence of childhood-onset type 1 diabetes in the Canarian population does not appear to be explained by a greater prevalence of high-risk class II HLA haplotypes in families with the disease. However, sample size limits the differences that can be detected in this study.

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关键词

Genetics,Type 1 diabetes mellitus,Epidemiology,Major histocompatibility complex,Haplotype,Human leucocyte antigen

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