1000 consecutive liver transplants. Descriptive analysis and evolution of a single center.

Between 1991 and 2013, 1000 liver transplantations were performed at Virgen del Rocio Hospital (Seville, Spain). A retrospective study was conducted, analyzing the characteristics of recipients and donors, indications, surgical technique, complications and survival in 2 different stages (1991–2002 vs 2003–2013) coinciding with the implementation of the MELD scale as a prioritization model. The most frequent indication was of hepatopathy of hepatocellular origin in 48.8%. There was a significant increase in the indications for hepatocarcinoma (8.6% and 24.1% P=.03), and the rate of retransplantation (5.9% vs 9.6%, P=.04). There was a change in the age of donation, going from 27.7 years in 1990 to 62.9 years in 2012 (P=.001). The percentage of patients who did not require blood transfusion doubled (6.16% vs 14.31%, P=.001). Survival of all patients after 1, 5 and 10 years was 77%, 63.5% and 51.3%, respectively.