Usefulness of the Finet Law to Guide Stent Size Selection in Ostial Left Main Stenting: Comparison with Standard Angiographic Estimation

Backgrounds: Intravascular ultrasound has been suggested to optimize stent diameter and length in Left Main (LM) procedures, but in the real-world ostial LM stenting is often accomplished with angiography only guidance. The Find law which regulates the fractal geometry of human bifurcation has the potential to increase the accuracy of stent-sizing. To retrospectively evaluating the impact on outcomes of the addition of Fine( Law to standard quantitative coronary angiography (QCA) in guiding stent selection of ostial LM stenting compared to standard angiography estimation. Methods: We retrospectively evaluated the clinical and instrumental records of patients with isolated ostial LM disease and bypass surgery contraindications or refusal as determined by the local Heart Team who received stenting from 1 January 2012 to 1 January 2017 at Rovigo General Hospital. Patients were discrimined on the basis of the addition to QCA angiographic evaluation of the Finet-law. Results: Seventy-three patients (45 males, mean age 69.9 +/- 10.9 years old) ostial LM stenting, 36 patients using QCA and Finet law (QCA-Finet) and 37 using standard QCA angiographic (QCA-angio) evaluation of the vessel diameter. By QCA, vessel size, mean stent diameter at implantation and after post-dilatation were dearly bigger in the QCA+ Finet than QCA-angio (4.4 +/- 0.8 and 3.8 +/- 0.7, p < 0.001). At a mean follow-up of 5.0 +/- 0.4 years, cardiovascular mortality and cardiovascular events incidence were higher in QCA-angio compared to QCA+Finet group of patients. Conclusions: Our study suggested that adding the Finet law to standard angiography estimation of the LM stent size may improve long-term outcomes. (C) 2018 Elsevier Inc. All rights reserved.