The Map and the Territory: Mapping the Territory Regulated by Serotonergic Signaling at Striatal Projection Neurons

In this issue of Neuron, Cavaccini et al. (2018) identify and thoroughly describe a previously unknown role for hyper-localized serotonergic signaling in the modulation of striatal projection neuron plasticity using electrophysiological, chemogenetic, and optogenetic approaches in addition to advanced imaging technology.