Brain stimulation patterns emulating endogenous thalamocortical input to parvalbumin-expressing interneurons reduce nociception in mice.

Yeowool Huh,Dahee Jung,Taeyoon Seo,Sukkyu Sun,Su Hyun Kim,Hyewhon Rhim,Sooyoung Chung,Chong-Hyun Kim,Youngwoo Kwon,Marom Bikson,Yong-An Chung,Jeansok J Kim,Jeiwon Cho

Brain Stimulation（2018）

引用 5|浏览26

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摘要

•Electrical stimulation mimicking thalamic bursts activate cortical PV interneurons.•Selective optical activation of PV interneurons reduces nociceptive behaviors.•TMS mimicking ‘Thalamic burst’ reduces nociceptive behaviors in mice.

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关键词

Electrical therapy,rTMS,Thalamic bursting,Nociception,Parvalbumin interneurons,Sensory gating,Bioelectric medicine

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