What Do You Get from DNA-Encoded Libraries?

ACS medicinal chemistry letters（2018）

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摘要

Use of DNA-encoded libraries (DELs) in the pharmaceutical industry has rapidly increased. We discuss what to expect when you run a DEL screen and contemplate guidelines for library design. Additionally, we consider some visionary work and extrapolate to the future.

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关键词

DNA-encoded libraries,screening,drug discovery,molecular diversity,combinatorial chemistry,microfluidics

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