A Prospective Phase 2 Study Evaluating Safety and Efficacy of Combining Stereotactic Body Radiation Therapy With Heat-based Ablation for Centrally Located Lung Tumors.

Kiri A Sandler,Fereidoun Abtin,Robert Suh,Ryan R Cook,Carol Felix,Jay M Lee,Edward B Garon,Jeffrey Wu,Elaine M Luterstein,Nzhde Agazaryan,Stephen E Tenn,Chul Lee,Michael L Steinberg,Percy Lee

International Journal of Radiation Oncology*Biology*Physics（2018）

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摘要

Combining SBRT and HBA for centrally located lung tumors offers reasonable local control and toxicity despite the anatomic challenges of this location. HBA may be a reasonable supplement to SBRT when trachea and bronchus, large vessel, or esophageal constraints cannot be met with full-dose SBRT and a biologically effective dose < 100 Gy is delivered because of an ultra-central location or large tumor size.

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关键词

stereotactic body radiation therapy,centrally located lung tumors,lung tumors,ablation,heat-based

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