Set up of a protocol for rat plasma peptidomics in hemorrhagic shock model in presence of heparin.

Elisa Maffioli,Federico Aletti,Fabiana Santagata,Armando Negri,Marco H Santamaria,Frank A De Lano,Erik B Kistler, Geert W Schmid-Schönbein,Gabriella Tedeschi

EuPA Open Proteomics（2016）

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摘要

•A protocol for peptidome plasma analysis has been set up.•The presence of heparin did not affect peptides detection in plasma specimens.•Plasma displays an increase in peptides after hemorrhagic shock.

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关键词

Peptidomics,Heparin,Hemorrhagic shock,Proteolysis,Mass spectrometry

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