All-trans retinoic acid improves the viability of ischemic skin flaps in diabetic rat models.

Zhenjun Weng,Chunyang Wang,Cheng Zhang,Jia Xu,Yimin Chai,Yachao Jia,Pei Han,Gen Wen

Diabetes Research and Clinical Practice（2018）

引用 8|浏览11

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摘要

ATRA could notably exert preventive effects against skin flap necrosis and promote neovascularization in diabetic rats, which may partially through elevating the expression of ANG2 and VEGF, and augmenting EPC mobilization.

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关键词

Skin flap survival,Diabetic rats,All-trans retinoic acid,Endothelial progenitor cells,Neovascularization

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