Cathelicidin Related Antimicrobial Peptide (CRAMP) Enhances Bone Marrow Cell Retention and Attenuates Cardiac Dysfunction in a Mouse Model of Myocardial Infarction.

Stem cell reviews(2018)

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摘要
Cathelicidins enhance BMMNC retention and recruitment after intramyocardial administration post-AMI resulting in improvements in heart physiology and recovery. Therapies employing these strategies may represent an attractive method for improving outcomes of regenerative therapies in human studies.
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关键词
Bone marrow derived mononuclear cells (BMMNCs),Cathelicidin related antimicrobial peptide (CRAMP),LL-37,Myocardial infarction,Regeneration,Stem cells homing
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