The evolution of adaptiveness: balancing speed and evidence

Hans-Georg Eichler, Richard Barker, Nicola Bedlington,Jacoline C. Bouvy, André W. Broekmans,Anna Bucsics,Francesca Cerreta,Solange Corriol-Rohou, Alicia Granados, Yann Le Cam,Ad Schuurman

NATURE REVIEWS DRUG DISCOVERY（2018）

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摘要

'Adaptive' approaches to bringing drugs to market have been widely discussed in recent years. Here, we describe the evolution of the adaptive approach and of concepts developed by ADAPT SMART, a multi-stakeholder consortium funded by the European Innovative Medicines Initiative.

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关键词

Clinical trials,Drug regulation,Biomedicine,general,Pharmacology/Toxicology,Biotechnology,Medicinal Chemistry,Molecular Medicine,Cancer Research

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