D-dimer in Adolescent Pulmonary Embolism.

This study represents the largest available cohort of adolescent patients examining the diagnostic value of D-dimer for PE. Our results indicate that depending on the threshold selected, D-dimer can be a sensitive test for PE in adolescents and that discriminative value is higher for a cutoff of 750 ng/ml than 500 ng/ml. Prospective studies investigating the diagnostic value of D-dimer and a clinical decision rule for PE in pediatrics are needed. This article is protected by copyright. All rights reserved.