Mobius Sequence With Central Hypoventilation In A Neonate After Failed Elective Medical Termination Of Pregnancy

ARCHIVES OF DISEASE IN CHILDHOOD-FETAL AND NEONATAL EDITION(2019)

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摘要
In utero misoprostol exposure has been associated with Mobius sequence and terminal transverse limb defects following failed medical termination of pregnancy.1 Mobius sequence affects 1 in 50 000 live births; there is congenital facial or abducens nerve palsy and a variable association with central hypoventilation and transverse limb defects.2 3 Pathogenesis is presumed vascular disruption and hypoxic injury secondary to misoprostol-induced uterine contractions between 6 and …
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关键词
dysmorphology,fetal medicine,neonatology,neurology,toxicology
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