UK Renal Registry 19th Annual Report: Chapter 9 Clinical, Haematological and Biochemical Parameters in Patients on Renal Replacement Therapy in Paediatric Centres in the UK in 2015: National and Centre-specific Analyses.

The median height z-score for paediatric patients on dialysis in 2015 was -1.8 and for those with a functioning transplant -1.2. Children transplanted before the age of 12 years improved their height z-score over the subsequent five years, whereas those older than 12 years maintained their height z-score, with all transplanted patients having a similar median height z-score after five years of starting renal replacement therapy (RRT). The median weight z-score for children on dialysis in 2015 was -1.1, whereas children with a functioning transplant had a near normal weight for age and sex with a median z-score of -0.2. Of those with data, 75% of the prevalent paediatric RRT population in 2015 had one or more 'traditional' risk factors for cardiovascular disease, with 7% having all three risk factors present. For the 12 centres reporting quarterly laboratory data, the median creatinine in transplant patients in 2015 was 79 mmol/L; on average, dialysis patients in 2015 had normal anaemia and acidosis parameters and evidence of secondary hyperparathyroidism, with a median parathyroid hormone (PTH) of 21 pmol/L For transplant patients, 82% achieved the systolic blood pressure (SBP) standard and 93% achieved the haemoglobin standard in 2015. For haemodialysis patients, 63% achieved the SBP standard, 73% achieved the haemoglobin standard, 76% achieved the calcium standard, 48% achieved the phosphate standard and 45% achieved the PTH standard in 2015. For peritoneal dialysis patients, 63% achieved the SBP standard, 75% achieved the haemoglobin standard, 70% achieved the calcium standard, 52% achieved the phosphate standard and 32% achieved the PTH standard in 2015.