The correlation of asymmetrical functional connectivity with cognition and reperfusion in carotid stenosis patients.

•Cerebral hypoconnectivity on functional MRI is lateralized to carotid stenosis side.•Cerebral hyperconnectivity is in regions contralateral to carotid stenosis side.•Abnormal connectivity gradually returns back to normal after carotid stenting.•Hypo- and hyper-connectivity associate with poor cognitive performances.•Hyperconnectivity could be served as a compensation for neural challenge.