Polysaccharides extracted from Phellinus linteus ameliorate high-fat high-fructose diet induced insulin resistance in mice.

Han Feng,Shijie Zhang,Jennifer Man-Fan Wan, Lifeng Gui,Mengcheng Ruan,Na Li,Hongyu Zhang,Zhiguo Liu,Hualin Wang

Carbohydrate Polymers（2018）

引用 55|浏览17

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摘要

•PLP restored vitamin B12 level, due to accumulation of VB12 synthesis related gut microbiota.•PLP modified the hepatic S-adenosyl methionine metabolism and rescued the hepatic PC/PE ratio.•PLP improved insulin sensitivity, hepatic FOXO signaling pathway may be involved.

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关键词

DEG,DGGE,FPKM,GO,HCY,HFD,NAFLD,PC,PE,PLP,SAM,SAH,T2DM,TC,TG,VB12

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