Truncated Core/NS3 Fusion Protein of HCV Adjuvanted with Outer Membrane Vesicles of Neisseria Meningitidis Serogroup B: Potent Inducer of the Murine Immune System

Iranian biomedical journal(2019)

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摘要
NMB OMVs were able to increase Th1 immune responses dramatically more than MF59 and Freund’s CIA. The formulation of rC/N with NMB OMVs showed its ability to induce Th1, Th2, and Th17 immune responses. rC/N-NMB OMVs is a promising approach for the development of an HCV therapeutic vaccine.
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关键词
Adjuvants,Hepatitis C virus,Immunization,Vaccines
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