Truncated Core/NS3 Fusion Protein of HCV Adjuvanted with Outer Membrane Vesicles of Neisseria Meningitidis Serogroup B: Potent Inducer of the Murine Immune System
Iranian biomedical journal(2019)
摘要
NMB OMVs were able to increase Th1 immune responses dramatically more than MF59 and Freund’s CIA. The formulation of rC/N with NMB OMVs showed its ability to induce Th1, Th2, and Th17 immune responses. rC/N-NMB OMVs is a promising approach for the development of an HCV therapeutic vaccine.
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关键词
Adjuvants,Hepatitis C virus,Immunization,Vaccines
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