Simulating human sleep spindle MEG and EEG from ion channel and circuit level dynamics.

B Q Rosen,G P Krishnan,P Sanda,M Komarov,T Sejnowski,N Rulkov,I Ulbert,L Eross,J Madsen,O Devinsky,W Doyle,D Fabo,S Cash,M Bazhenov,E Halgren

Journal of Neuroscience Methods（2019）

引用 6|浏览61

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摘要

•Novel multiscale modeling framework generates sleep spindles.•Neural model embedded in cortex and cranial tissues reconstructed from MRI.•Thalamocortical model of neural spindles linked to biophysical model of M/EEG.•Simulated M/EEG spindles similar in amplitude and topography to empirical examples.•Simulated spindles with more core-dominant cortical activity are more MEG weighted.

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关键词

MEG,EEG,Forward model,Sleep,Spindle,Thalamus,Cortex,Human

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