A binary matrix for the rapid detection and characterization of small-molecule cardiovascular drugs by MALDI-MS and MS/MS.

Jinlan Dong,Wenjing Ning,Daniel J Mans, Jamie D Mans

ANALYTICAL METHODS（2018）

引用 3|浏览8

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摘要

A mixture of alpha-cyano-4-hydroxycinnamic acid and 1,5-diaminonaphthalene was discovered as a novel binary matrix for the qualitative analysis of 14 small-molecule (similar to 250-550 Da) cardiovascular drugs by matrix-assisted laser desorption/ionization mass spectrometry (MALDI-MS) and MS/MS in either positive or negative ion mode.

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