Low Level Expression of the Mitochondrial Antiviral Signaling Protein (MAVS) Associated with Long-Term Nonprogression in SIV-infected Rhesus Macaques.
Virology journal（2018）
Abstract
Abnormally increased immune activation is one of the main pathological features of acquired immunodeficiency syndrome (AIDS). This study aimed to determine whether long-term nonprogression (LTNP) suppresses the upregulation of immune activation and to elucidate the mechanisms whereby the LTNP state is maintained.
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Key words
Simian immunodeficiency virus,Disease progression,Activation,Inflammation,LTNP,MAVS
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