Maternal Immune Activation Alters Brain Microrna Expression in Mouse Offspring

Jun-Sang Sunwoo,Daejong Jeon,Soon-Tae Lee,Jangsup Moon,Jung-Suk Yu,Dong-Kyu Park,Ji-Yeon Bae,Doo Young Lee,Sangwoo Kim,Keun-Hwa Jung,Kyung-Il Park,Ki-Young Jung,Manho Kim,Sang Kun Lee,Kon Chu

Annals of clinical and translational neurology（2018）

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摘要

Maternal immune activation (MIA) is associated with an increased risk of autism spectrum disorder (ASD) in offspring. Herein, we investigate the altered expression of microRNAs (miRNA), and that of their target genes, in the brains of MIA mouse offspring.

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