Phase II study of induction chemotherapy with docetaxel, cisplatin, 5-fluorouracil followed by radioimmunotherapy with cetuximab and intensity-modulated radiotherapy in combination with a carbon ion boost for locally advanced tumors of the oro-, hypopharynx and larynx.

H Hauswald,A D Jensen,J Krauss,R Haselmann,K Lossner, S Hartmann,C Windemuth-Kieselbach,M W Münter,J Debus

Clinical and Translational Radiation Oncology（2018）

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摘要

•Trimodal approach with carbon ions was tolerable and promising.•No high-grade radiation adverse events were documented.•No adverse events resulted in death of patients.•Quality of life recovered for most aspects until the last follow-up visit.

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关键词

Particle therapy,Carbon ion therapy,Cetuximab,LAHNC,SCCHN,Head and neck cancer

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