Canine Influenza Virus A(H3N2) Clade with Antigenic Variation, China, 2016-2017.

Yanli Lyu,Shikai Song,Liwei Zhou,Guoxia Bing,Qian Wang,Haoran Sun,Mingyue Chen,Junyi Hu,Mingyang Wang,Honglei Sun,Juan Pu,Zhaofei Xia,Jinhua Liu,Yipeng Sun

EMERGING INFECTIOUS DISEASES（2019）

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摘要

During 2012-2017, we collected throat swabs from dogs in China to characterize canine influenza virus (CIV) A(H3N2) isolates. A new antigenically and genetically distinct CIV H3N2 clade possessing mutations associated with mammalian adaptation emerged in 2016 and replaced previously circulating strains. This clade probably poses a risk for zoonotic infection.

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关键词

China,H3N2,PB2,adaptation,antigenicity,canine influenza,dogs,evolution,influenza,influenza A virus,mammalian adaptations,respiratory infections,serology,surveillance,viruses,zoonoses

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