Synthesis, characterization, and cytotoxicity assessment of N-acetyl-l-cysteine capped ZnO nanoparticles as camptothecin delivery system.
Colloids and Surfaces B: Biointerfaces(2019)
摘要
•Camptothecin-loaded and N-acetyl-l-cysteine capped ZnO nanoparticles were prepared.•Resultant nanoparticles had double-layer structure with a diameter of ∼70 nm.•Drug-loaded nanoparticles had almost no hemolytic activity.•An augmented anticancer effect of nanoconjugate complex was concluded in A549.
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关键词
ZnO nanoparticles,N-acetyl-l-cysteine,Camptothecin,Surface functionalization,Cytotoxicity
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