Combined Clinical and Genetic Testing Algorithm for Cervical Cancer Diagnosis
Clinical epigenetics(2016)
摘要
Opportunistic screening in hospitals is widely used to effectively reduce the incidence rate of cervical cancer in China and other developing countries. This study aimed to identify clinical risk factor algorithms that combine gynecologic examination and molecular testing (paired box gene 1 (PAX1) or zinc finger protein 582 (ZNF582) methylation or HPV16/18) results to improve diagnostic accuracy.
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关键词
Biomarkers,Algorithm,DNA methylation,HPV16/18,Cervical cancer,ZNF582,PAX1
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