Pleural effusion with negative culture: a challenge for pneumococcal diagnosis in children.

Vinicius Pieta Perez,Juliana Caierão,Gilberto Bueno Fischer,Cícero Armídio Gomes Dias,Pedro Alves d'Azevedo

Diagnostic Microbiology and Infectious Disease（2016）

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摘要

•Culture independent methods are indicated in children with pleural effusion.•Results of BinaxNow and qPCR for S. pneumoniae show imperfect relationship.•Pleural qPCR is a valuable tool in diagnosis of pneumococci after antimicrobial therapy.

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关键词

Streptococcus pneumoniae,Pleural effusion,Real-time PCR,C-polysaccharide,Empyema

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