Immunoglobulin G4‐related Disease Presenting As a Pulmonary Nodule with an Irregular Margin

Tetsuyuki Okubo,Yumiko Oyamada,Masaya Kawada,Yo Kawarada,Shuji Kitashiro,Shunichi Okushiba

Respirology case reports（2016）

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摘要

We report a case of immunoglobulin G4 (IgG4)‐related lung disease presenting as a solitary pulmonary nodule with an irregular margin on computed tomography. The nodule showed a high standardized uptake value on positron emission tomography. A malignant pulmonary tumour could not be excluded. Middle lobectomy was performed. Histological analysis revealed marked lymphoplasmacytic infiltration and storiform fibrosis. Immunostaining indicated the presence of IgG4‐positive plasma cells. A definitive diagnosis of IgG4‐related disease was confirmed.

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关键词

Immunoglobulin G4-related disease,immunoglobulin G4-related lung disease,irregular margin,lung cancer,solitary pulmonary nodule

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